Reproductive Pharmacology Section 11- Phosphodiesterase type 5 inhibitors

TOPICS: Vardenafil, tadalafil, sildenafil, avanafil, pde-5 inhibitors, increased cgmp, prolongs smooth muscle relaxation in response to NO, increased blood flow into corpus cavernosum of penis, decreased pulmonary vascular resistance, relative vasodilation of pulmonary vasculature, erectile dysfunction, pulmonary hypertension, bph, headaches, flushing, cyanopia, dyspepsia, contraindicated with nitroglycerin due to risk of severe hypotension
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