Psychiatric Pharmacology Section 2- Neuroleptic Malignant Syndrome

TOPICS: Neuroleptic malignant syndrome, dopamine antagonism, antipsychotics (typical and atypical), genetic predisposition, 1-3 days after taking antipsychotics, muscle rigidity, rhabdomyolysis, high serum CK, myoglobin, myoglobinuria, urine a red or brown tint, renal failure, hyperthermia, diaphoresis, tachycardia, hypertension encephalopathy, hyporeflexia, dantrolene, prevents release of calcium from sarcoplasmic reticulum, benzodiazepines, dopamine agonists

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