Psychiatric Pharmacology Section 15- Typical Antipsychotic

TOPICS: First generation (typical) antipsychotics, haloperidol, pimozide, trifluoperazine, fluphenazine, thioridazine, retinal deposits, chlorpromazine, corneal deposits, blocking the d2 receptor, dementia, increases camp, psychosis, huntington's disease, tourette syndrome, obsessive compulsive disorder (ocd), 1°positive symptoms in schizophrenia, delirium, bipolar disorder, haloperidol, trifluoperazine and fluphenazine are the most potent and come with the highest risk for eps, increased risk for antihistamine effects (eg, sedation), increased risk for anticholinergic effects (hot, dry, urinary retention), increased risk for alpha-blockade, postural hypotension, weight gain, hyperglycemia, qt prolongation, torsades de pointes, hyperprolactinemia and galactorrhea, oligomenorrhea and/or amenorrhea, dyslipidemia, lipid soluble, long half life



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