Pharmacology

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Adrenergic Receptors Section 1 - Adrenergic Receptors (26:05)
TOPICS: Alpha-1 receptors, gpcr, gq protein, phospholipase c activation, pip2, ip3, dag, pkc, calcium, pupillary dilator muscle contraction, mydriasis (dilated pupils), alpha-1 stimulation, vascular smooth muscle contraction, vasoconstriction, internal urethral sphincter muscle contraction, alpha-2 receptors, gq protein, adenylate cyclase, camp, norepinephrine (ne) release, aqueous humor production, intraocular pressure, insulin release, lipolysis, platelet aggregation, beta1, beta2, beta3, gs protein, contractility, inotropy, inotropic, chronotropy,chronotropic, renin, lipolysis, vasodilation, skeletal muscle, coronary arteries, bronchodilation/bronchial relaxation, potassium, glycogenolysis, uterine tone, detrusor smooth muscle, bladder capacity, thermogenesis
Epinephrine and Norepinephrine Section 2 - Epinephrine and Norepinephrine (25:19)
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Alpha Agonists Section 3 - Alpha Agonists (18:16)
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Beta Agonists Section 4 - Beta Agonists (16:47)
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Alpha Blockers Section 5 - Alpha Blockers (20:21)
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Beta Blockers Section 6 - Beta Blockers (19:03)
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Nicotinic Acetylcholine ReceptorsSection 7 - Nicotinic Acetylcholine Receptors (7:35)
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Muscarinic Acetylcholine ReceptorsSection 8 - Muscarinic Acetylcholine Receptors (15:28)
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Direct Cholinergic AgonistsSection 9 - Direct Cholinergic Agonists (19:59)
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Indirect Cholinergic AgonistsSection 10 - Indirect Cholinergic Agonists (20:44)
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Anticholinesterase PoisoningSection 11 - Anticholinesterase Poisoning (16:14)
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Muscarinic AntagonistsSection 12 - Muscarinic Antagonists (12:53)
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AtropineSection 13 - Atropine (14:02)
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Dopamine, Histamine, and Vasopressin ReceptorsSection 14 - Dopamine, Histamine, and Vasopressin Receptors(19:32)
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cyclosporineSection 1 - Cyclosporine (7:36)
TOPICS: Cyclosporine, cyclophilin, calcineurin, immunomodulator, blocks t-cell, blocks IL-2 gene, block transcription, rheumatoid arthritis, treatment, psoriasis, acute transplant rejection, gingival hyperplasia, hypertension, gout, risk of infection, risk of malignancy, hyperlipidemia, neurotoxicity, tremor, nephrotoxicity, renal tubular acidosis, RTA
tacrolimusSection 2 - Tacrolimus (4:57)
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sirolimusSection 3 - Sirolimus (7:47)
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basiliximabSection 4 - Basiliximab (4:03)
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azathioprineSection 5 - Azathioprine and 6 MP (11:26)
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mycophenolateSection 6 - Mycophenolate (5:27)
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glucocorticoidsSection 7 - Glucocorticoids (14:56)
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bone marrow stimulationSection 8 - Bone Marrow Stimulation (6:38)
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interferonsSection 9 - Interferons Alpha, Beta and Gamma (8:39)
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penicillinSection 1 - Penicillin G,V (9:43)
TOPICS: Penicillin, beta lactam rings, pbp, penicillin binding proteins, cell wall cross linking, peptidoglycan, resistance, beta lactamases, syphilis, actinomyces, neisseria meningitidis, strep agalactiae, intrapartum period, rheumatic fever, strep pyogenes, m protein, strep pharyngitis, strep pneumoniae, hypersensitivity, autoimmune hemolytic anemia, allergic reactions, acute interstitial nephritis, serum sickness, stevens johnson syndrome
aminopenicillinsSection 2 - Amoxicillin and Ampicillin (11:17)
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antistaphSection 3 - Antistaphylococcal Penicillins (5:19)
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antipseudomonalSection 4 - Antipseudomonal Penicillins (8:02)
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cephalosporinsSection 5 - Cephalosporins (18:18)
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carbapenemsSection 6 - Carbapenems (6:42)
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monobactamsSection 7 - Monobactams (6:16)
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vancomycinSection 8 - Vancomycin (10:38)
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bacitracinSection 9 - Bacitracin (2:33)
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aminoglycosidesSection 10 - Aminoglycosides (9:55)
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tetracyclinesSection 11 - Tetracyclines (9:41)
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glycylocyclinesSection 12 - Glycylcyclines (5:37)
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chloramphenicolSection 13 - Chloramphenicol (9:08)
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clindamycinSection 14 - Clindamycin (7:37)
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linezolidSection 15 - Linezolid (4:42)
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macrolidesSection 16 - Macrolides (11:44)
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polymyxinsSection 17 - Polymyxins (4:57)
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TrimethoprimSection 18- Trimethoprim and Sulfonamides (12:34)
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fluoroquinolonesSection 19 - Fluoroquinolones (8:14)
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daptomycinSection 20 - Daptomycin (5:46)
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metronidazoleSection 21 - Metronidazole (5:59)
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dapsoneSection 22 - Dapsone, Rifamycins, Clofazimine (Leprosy Drugs) (11:27)
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isoniazidSection 23 - Isoniazid (RIPE) (9:18)
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ethambutolSection 24 - Ethambutol and Pyrazinamide (6:46)
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amphotericin BSection 1 - Amphotericin B, Nystatin, and Flucytosine (13:09)
TOPICS: Amphotericin b, ergosterol, electrolyte leakage, cryptococcus, flucytosine, 5 fluorouracil, bone marrow suppression, intrathecal, meningitis, coccidioidomycosis, blastomycosis, histoplasmosis, candida, mucor, human cholesterol, fever, chills, kidney damage, hydrated, magnesium, potassium, arrhythmia, anemia, hypotension, liposomal, thrombophlebitis, nystatin, candida, topical, esophageal and oral candidiasis
azolesSection 2 - Azoles (11:23)
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terbinafineSection 3 - Terbinafine (3:47)
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echinocandinsSection 4 - Echinocandins (3:44)
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griseofulvinSection 5 - Griseofulvin (5:48)
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malathionSection 1 - Malathion, Permethrin, and Lindane (5:46)
TOPICS: Neuronal synapse, acetylcholinesterase, malathion, neurotoxicity, conjunctivitis, permethrin, sodium channel, lindane, gaba, ataxia, burning sensation, pediculus infections, lice, scabies
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hypertension treatmentSection 1 - Hypertension Treatment (17:39)
TOPICS: Primary hypertension, essential hypertension, thiazide, ace inhibitors, angiotensin receptor blockers, calcium channel blockers, asthma, cough, bronchoconstriction, cardioselective beta blockers, diabetes mellitus, D diabetic nephropathy, hypoglycemia, pregnancy, hydralazine, labetalol, methyldopa, nifedipine, heart failure, loop diuretics, sacubitril, cardiogenic shock, decompensated heart failure, aldosterone antagonists
calcium channelSection 2 - Calcium Channel Blockers (13:37)
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hydralazineSection 3 - Hydralazine (8:19)
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fenoldopamSection 4 - Fenoldopam and Nitroprusside (9:50)
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nitratesSection 5 - Nitrates (13:13)
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ranolazineSection 6 - Ranolazine (4:32)
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milrinoneSection 7 - Milrinone (6:19)
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sacubitrilSection 8 - Sacubitril (8:49)
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statinsSection 9 - Statins (8:36)
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bile acid resinsSection 10 - Bile Acid Resins (6:56)
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ezetimibeSection 11 - Ezetimibe (3:50)
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fibratesSection 12 - Fibrates (9:02)
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niacinSection 13 - Niacin (7:57)
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PCSK9Section 14 - PCSK9 Inhibitors (6:22)
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fish oilSection 15 - Fish Oil, and Omega-3 Fatty Acids (3:57)
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digoxinSection 16 - Digoxin (12:52)
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IA IB IC antiarrhythmicsSection 17 - Class IA, IB, and IC Antiarrhythmics (23:51)
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II antiarrhythmicsSection 18 - Class II Antiarrhythmics (23:08)
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III antiarrhymthmicsSection 19 - Class III Antiarrhythmics (16:28)
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IV antiarrhythmicsSection 20 - Class IV Antiarrhythmics (14:18)
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antiarrhythmicsSection 21 - Other Antiarrhythmics (Adenosine and Magnesium) (15:25)
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ivabradineSection 22 - Ivabradine (7:18)
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insuin prepSection 1 - Insulin Preparations (8:16)
TOPICS: Regular insulin, 2-3 hour peak, diabetic ketoacidosis, hyperkalemia, stress hyperglycemia, rapid acting preparations, 1 hour peak, lispro, aspart, glulisine, nph, intermediary acting, 4-10 hour peak, long acting preparations, detemir, glargine, insulin receptor, tyrosine kinase receptor, glycogen, protein synthesis, triglyceride storage, potassium, hypoglycemia, lipodystrophy, weight gain, hypersensitivity
biguanidesSection 2 - Biguanides (Metformin) (7:05)
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glitazonesSection 3 - Glitazones/Thiazolidinediones (7:13)
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sulfonylureasSection 4 - Sulfonylureas and Meglitinides (7:36)
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amylinSection 5 - Amylin analogs and GLP-1 analogs (7:17)
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DPP-4Section 6 - DPP-4 inhibitors (7:42)
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SGLT2Section 7 - Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors (7:04)
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alpha glucosidaseSection 8 - Alpha-glucosidase Inhibitors (5:02)
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thionamidesSection 9 - Thionamides (8:52)
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levothyroxineSection 10 - Levothyroxine and Liothyronine (4:07)
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cinacalcetSection 11 - Cinacalcet (5:25)
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sevelamerSection 12 - Sevelamer (3:08)
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ADHSection 13 - ADH-related Drugs (9:28)
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fludrocortisoneSection 14 - Fludrocortisone (2:08)
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heparin fondaparinux mnemonicSection 1 - Heparin, LMWHs, and Fondaparinux (24:36)
TOPICS: Heparin, anticoagulant, antithrombin III, factor IIa, thrombin, factor Xa, ptt, low molecular weight heparin, lmwh, enoxaparin, dalteparin, fibrin meshwork, fondaparinux, synthetic heparin, renally excreted, bioavailability, half life, pulmonary embolism, acute coronary syndromes, deep venous thrombosis, myocardial infarction, pregnancy, bleeding, thrombocytopenia, hit, platelet count, osteoporosis, protamine sulfate, severe uncontrolled hypertension, uncontrolled active bleed, kidney disease
Direct Thrombin mnemonicSection 2 - Direct Thrombin Inhibitors and Direct Factor Xa Inhibitors (16:37)
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Warfarin mnemonicSection 3 - Warfarin (33:25)
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Thrombolytics mnemonicSection 4 - Thrombolytics (13:31)
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ADP Receptor Inhibitors mnemonicSection 5 - ADP Receptor Inhibitors (11:26)
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Antiplatelet PDE mnemonicSection 6 - Antiplatelet PDE Inhibitors (Cilastazol and Dipyridamole) (16:45)
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Glycoprotein mnemonicSection 7 - Glycoprotein IIb/IIIa Inhibitors (8:18)
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Bleomycin Dactinomycin Doxorubicin and Daunorubicin mnemonicSection 8 - Bleomycin, Dactinomycin, Doxorubicin and Daunorubicin (20:50)
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Cladribine and Cytarabine mnemonicSection 9 - Cladribine and Cytarabine (14:16)
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5-Fluorouracil Methotrexate Leucovorin and Hydroxyurea mnemonicSection 10 - 5-Fluorouracil, Methotrexate, Leucovorin, and Hydroxyurea (28:08)
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Busulfan Cyclophosphamide Ifosfamide and Nitrosureas mnemonicSection 11 - Busulfan, Cyclophosphamide, Ifosfamide, and Nitrosureas (20:43)
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Procarbazine mnemonicSection 12 - Procarbazine (8:13)
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Microtubule Inhibitors mnemonicSection 13 - Microtubule Inhibitors (13:48)
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Cisplatin Carboplatin Oxaliplatin mnemonicSection 14 - Cisplatin, Carboplatin, Oxaliplatin (and Amifostine) (10:28)
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Etoposide Teniposide Irinotecan and Topotecan mnemonicSection 15 - Etoposide, Teniposide, Irinotecan and Topotecan (15:15)
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Imatinib Dasatinib Nilotinib Erlotinib Dabranefib and Vemurafenib mnemonicSection 16 - Imatinib, Dasatinib, Nilotinib, Erlotinib, Dabranefib, and Vemurafenib (19:10)
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Rituximab Bevacizumab Alemtuzumab Cetuximab Panitumumab and Trastuzumab mnemonicSection 17 - Rituximab, Bevacizumab, Alemtuzumab, Cetuximab, Panitumumab, and Trastuzumab (25:47)
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Bortezomib and Carfilzomib mnemonicSection 18 - Bortezomib and Carfilzomib (6:48)
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Rasburicase mnemonicSection 19 - Rasburicase (6:51)
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epilepsy ethosuximideSection 1 - Epilepsy: Ethosuximide (5:12)
TOPICS: Ethosuximide, blocks thalamic voltage gated T type calcium channels, first line for absence seizures, spike and wave pattern, frequency of 2.5-3.5 Hz, fatigue, GI distress, headache, itching (urticaria), Stevens Johnson syndrome
epilepsy lamotrigineSection 2 - Epilepsy: Lamotrigine, Levetiracetam, Topiramate and Valproic Acid (23:27)
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epilepsy carbamazepineSection 3 - Epilepsy: Carbamazepine, Phenytoin, Gabapentin, Tiagabine, (28:51)
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barbituratesSection 4 - Barbiturates (10:31)
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benzodiazepinesSection 5 - Benzodiazepines (15:05)
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nonbenzodiazepineSection 6 - Nonbenzodiazepine Hypnotics (8:55)
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suvorexantSection 7 - Suvorexant (6:18)
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ramelteonSection 8 - Ramelteon (4:02)
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triptansSection 9 - Triptans (8:24)
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dopamine agonistsSection 10 - Dopamine Agonists (9:00)
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carbidopa/levodopaSection 11 - Carbidopa/Levodopa, COMT Inhibitors (Entacapone, Tolcapone) (14:07)
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dopamine availabilitySection 12 - Dopamine Availability (Amantadine) (4:23)
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alzheimer disease treatmentSection 13 - Alzheimer Disease Treatment (Donepezil, Rivastigmine, Galantamine, Memantine) (6:10)
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riluzoleSection 14 - Riluzole (4:13)
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tetrabenazineSection 15 - Tetrabenazine (3:47)
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inhaled anestheticsSection 16 - Inhaled Anesthetics (8:46)
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IV anestheticsSection 17 - IV Anesthetics (13:39)
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local anestheticsSection 18 - Local Anesthetics (16:35)
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neuromuscular blocking drugsSection 19 - Neuromuscular Blocking Drugs (19:18)
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baclofenSection 20 - Baclofen, Tizanidine, and Cyclobenzaprine (6:28)
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opioid clinicalSection 21 - Opioid Clinical Use, Mechanism and Overdose (18:58)
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mixed agonist opioidsSection 22 - Mixed Agonist and Antagonist Opioids (Nalbuphine, Pentazocine, Butorphanol) (9:56)
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tramadolSection 23 - Tramadol (5:22)
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glaucoma decrease synthesisSection 24 - Glaucoma: Decrease Aqueous Humor Synthesis (13:59)
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glaucoma increaseSection 25 - Glaucoma: Increase Outflow of Aqueous Humor (14:49)
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serotoninSection 1 - Serotonin Syndrome (5:50)
TOPICS: Serotonin syndrome, 5-HT, caused by any drug that increases serotonin, clonus, hyperreflexia, hypertonia, tremors, seizures, autonomic instability, hyperthermia, diaphoresis, diarrhea, altered mental status, cyproheptadine, 5-HT2 receptor antagonist
neurolepticSection 2 - Neuroleptic Malignant Syndrome (9:38)
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extrapyramidalSection 3 - Extrapyramidal Symptoms (including Acute Dystonia) (11:49)
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CNS depressantsSection 4 - CNS Depressants Overview (8:12)
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alcoholSection 5 - Alcohol (13:08)
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CNS stimulantsSection 6 - CNS Stimulants Overview (8:00)
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amphetaminesSection 7 - Amphetamines and Methylphenidate (12:05)
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caffeineSection 8 - Caffeine (3:37)
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cocaineSection 9 - Cocaine (14:20)
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nicotineSection 10 - Nicotine (6:11)
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LSDSection 11 - LSD (2:29)
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marijuanaSection 12 - Marijuana (7:10)
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MDMASection 13 - MDMA (7:19)
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PCPSection 14 - PCP (4:40)
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typical antipsychoticSection 15 - Typical Antipsychotic (13:57)
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atypical antipsychoticSection 16 - Atypical Antipsychotic (13:17)
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lithiumSection 17 - Lithium (11:20)
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buspironeSection 18 - Buspirone (4:40)
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SSRIsSection 19 - SSRIs (11:15)
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SNRIsSection 20 - SNRIs (9:21)
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tricyclic antidepressantsSection 21 - Tricyclic Antidepressants (12:41)
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monoamineSection 22 - Monoamine Oxidase Inhibitors (12:13)
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bupropionSection 23 - Bupropion (6:34)
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mirtazapineSection 24 - Mirtazapine (7:13)
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trazodoneSection 25 - Trazodone (7:13)
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vareniclineSection 26 - Varenicline (4:50)
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vilazodoneSection 27 - Vilazodone (6:18)
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vortioxetineSection 28 - Vortioxetine (7:41)
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antidepressant discontinuationSection 29 - Antidepressant Discontinuation Syndrome (3:37)
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opioid withdrawalSection 30- Opioid Withdrawal, Detoxification and Relapse Prevention (15:19)
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leuprolideSection 1 - Leuprolide, Goserelin and Degarelix (13:10)
TOPICS: Goserelin, leuprolide, gnrh analogs, pulsatile fashion they acts as gnrh agonists, continuous use they act as gnrh antagonists, decreased lh and fsh, low testosterone, leydig cells, decreased estrogen synthesis, granulosa cells, uterine fibroids, endometriosis, precocious puberty, prostatic carcinoma, infertility, hypogonadism, decrease libido, erectile dysfunction, nausea, vomiting, degarelix, gnrh antagonist, hot flashes, liver toxicity
estrogensSection 2 - Estrogens and Hormone Replacement Therapy (11:49)
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raloxifeneSection 3 - Raloxifene, Clomiphene, Tamoxifen (12:31)
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aromataseSection 4 - Aromatase Inhibitors (5:17)
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progestinsSection 5 - Progestins & Antiprogestins (13:53)
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contraception IUDsSection 6 - Combined Contraception and Copper IUDs (12:04)
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tocolyticsSection 7 - Tocolytics (4:22)
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danazolSection 8 - Danazol (6:52)
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testosteroneSection 9- Testosterone, Methyltestosterone (7:32)
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antiandrogensSection 10 - Antiandrogens (12:40)
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phosphodiesteraseSection 11 - Phosphodiesterase type 5 inhibitors (10:22)
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micturition controlSection 12 - Micturition Control (14:22)
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minoxidilSection 13 - Minoxidil (6:56)
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histamine 1 blockersSection 1 - Histamine-1 Blockers (9:51)
TOPICS: H-1 blockers, first generation H1 blockers, blood brain barrier, more side effects, diphenhydramine, chlorpheniramine, dimenhydrinate, doxylamine, treat allergies, motion sickness, sleep aid, sedation, antimuscarinic effects, anti alpha adrenergic effects, hypotension, tachycardia, second generation H1 blockers, loratadine, fexofenadine, desloratadine, cetirizine, treat allergies, less sedating
dextromethorphanSection 2 - Dextromethorphan and Guaifenesin (4:25)
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n acetylocysteineSection 3 - N-acetylcysteine (1:56)
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pseudoephedrineSection 4 - Pseudoephedrine, Phenylephrine (11:09)
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pulmonarySection 5 - Pulmonary HTN Drugs (10:04)
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asthma treatmentSection 6 - Asthma Treatment (10:36)
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alternative asthmaSection 7 - Alternative Asthma Treatment (12:10)
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monoclonalSection 8 - Anti-IL-5 Monoclonal Therapy (4:52)
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