Neuro Pharmacology Section 4- Barbiturates

TOPICS: Barbiturates, phenobarbital, secobarbital, pentobarbital, thiopental, induce anesthesia, GABAa receptor, chloride channels being open for longer, anxiety, seizures, insomnia, CNS depression, respiratory depression, hypotension, bradycardia, decrease in REM sleep, decrease in delta wave (N3) sleep, dependence, high lipid solubility, delirium, life threatening cardiovascular collapse, induces cytochrome p450, contraindicated with alcohol ingestion, contraindications with benzodiazepines, contraindicated in porphyria

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