Neuro Pharmacology Section 3- Epilepsy: Carbamazepine, Phenytoin, Gabapentin, Tiagabine

TOPICS: Narrow spectrum antiepileptics, carbamazepine, inactivates sodium channels, generalized tonic clonic seizures, focal seizures, trigeminal neuralgia, nausea, diplopia, induces cytochrome p450, agranulocytosis, hyponatremia, edema, SIADH, aplastic anemia, teratogenic, cleft lip/palate, spina bifida, ataxia, hepatotoxicity, Stevens Johnson syndrome, phenytoin, inactivates sodium channels, zero order elimination, tonic clonic seizures, status epilepticus, focal seizures, gingival hyperplasia, Steven Johnson syndrome, DRESS syndrome, hirsutism, drug induced lupus, yellow brown skin, megaloblastic anemia, folate deficiency, osteopenia, peripheral neuropathy, teratogenic, fetal hydantoin syndrome, induces cytochrome p450, nystagmus, diplopia, ataxia, sedation, gabapentin, inhibits T and L type voltage gated calcium channels, focal seizure, peripheral neuropathy, postherpetic neuralgia, dry mouth, somnolence, nausea, ataxia, tiagabine, inhibiting GABA reuptake, increases GABA, focal seizures, nausea, vomiting, diarrhea, insomnia, weight changes, vigabatrin, inhibits GABA transaminase, increases GABA, refractory focal seizures, irreversible vision loss, black box warning
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