TOPICS: Baclofen, GABAb receptor agonist in spinal cord, decreases excitability of spinal reflexes, tizanidine, central alpha 2 agonist, monotherapy for treatment of spasticity, muscle spasticity, dystonia, multiple sclerosis, cerebral palsy, amyotrophic lateral sclerosis, cyclobenzaprine, relax muscles, brainstem, pain and muscle spasticity