Neuro Pharmacology Section 2- Epilepsy: Lamotrigine, Levetiracetam, Topiramate and Valproic Acid

TOPICS: Broad spectrum antiepileptics, focal seizures, tonic clonic seizures, lamotrigine, blocks voltage gated sodium channels, inhibits glutamate release, absence seizures, mood stabilizer in bipolar disorder, blurry vision, Stevens Johnson syndrome, hemophagocytic lymphohistiocytosis, black box warning, levetiracetam, SV2A receptor blocker, inhibits voltage gated calcium channels, modulate GABA and glutamate release, somnolence, nausea, psychiatric symptoms, changes in personality, headache, topiramate, blocks voltage gated sodium channels, binds to GABA A receptor, increases GABA, migraine prophylaxis, idiopathic intracranial hypertension, somnolence, kidney stones, glaucoma, weight loss, word finding difficulties, cognitive slowing, valproic acid, valproate, inhibits GABA transaminase, increases GABA, inactivates sodium channels, absence seizures, mood stabilizer in bipolar disorder, myoclonic seizures, migraine prophylaxis, GI upset, hepatotoxicity, teratogenic, neural tube defects, tremor, sedation, ataxia, alopecia, pancreatitis, agranulocytosis, weight gain
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