TOPICS: Multipotential hematopoietic stem cells, CD19, CD20, CD21, Epstein-Barr virus (EBV), VDJ recombination, B cell receptor development, B cell activation (proliferation), B cell maturation, somatic hypermutation, class switching, differentiation, affinity maturation, apoptosis, germinal center, mantle zone, cortex, paracortex, high endothelial venule (HEV), CD40, CD40L, CD4, T helper cell (Th), T cell dependent activation, T cell independent activation, plasma cell, spleen, bone marrow, major histocompatibility complex (MHC) class II, bone marrow, antigen activation, B cell development, heavy chain, light chain, mRNA, variable (V) DNA segment, diversity (D) DNA segment, joining (J) DNA segment, C region, transcription, translation, antibody, T cell dependent activation of B cells, cytokine secretion, T cell independent activation of B cells, B cell receptor (BCR), T cell receptor (TCR), T cell proliferation, T cell differentiation, antibody secretion, antigen activation of B cells, lymph nodes, IgG, IgA, IgE, memory cells, secondary follicle, antibody-mediated immune response, antibodies
