TOPICS: T cell differentiation and maturation, positive selection, thymic cortex, self-MHC, T cells, thymic epithelial cells, apoptosis, negative selection, CD4, CD8, T cell receptor (TCR), antigen presenting cell (APC), thymic medulla, self antigens, regulatory T cells (Treg), autoimmune regulator (AIRE) gene, autoimmune endocrine diseases, autoimmune polyendocrinopathy Candidiasis ectodermal dystrophy (APECED), candida, hypoparathyroidism, adrenal failure
