TOPICS: Platinum based agents, cross linking dna, "platin", cisplatin, carboplatin, oxaliplatin, cell cycle independent, testicular cancer, bladder cancer, lung cancer, colorectal cancer, ovarian cancer, myelosuppression, ototoxicity, central and peripheral neuropathy, fanconi syndrome, nausea, vomiting, nephrotoxicity, saline diuresis, amifostine