Hem/Onc Pharmacology Section 11 – Busulfan, Cyclophosphamide, Ifosfamide, and Nitrosureas

TOPICS: Alkylating agents, cross linking dna, guanine, impaired dna synthesis, busulfan, ablation of bone marrow, bone marrow transplantation, severe myelosuppression, pulmonary fibrosis, hyperpigmentation, cyclophosphamide, ifosfamide, liver bioactivation, cyp450, nitrogen mustards, lymphomas, solid tumors, leukemia, rheumatoid arthritis, lupus, severe nephrotic syndrome, myelosuppression, bladder cancer, siadh, hemorrhagic cystitis, mesna, hydration, encephalopathy, neurotoxic, fanconi syndrome, carmustine, lomustine, cytochrome p450, blood brain barrier, brain tumors, ataxia, dizziness, seizures
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