Endocrine Pathology Section 10- Adrenal Medulla

TOPICS: Chromaffin cells, neural crest, catecholamines (epinephrine and norepinephrine), pheochromocytoma, zellballen pattern, episodic hypertension, headache, sweating, tachycardia, tremor, shortness of breath, increased catecholamines, metanephrines, vanillylmandelic acid (VMA), adrenalectomy, phenoxybenzamine (irreversible alpha-blocker) followed by beta-blocker, rule of 10s, 10% bilateral, 10% familial, 10% malignant, 10% located outside of adrenal medulla (eg, bladder wall), MEN 2A and 2B, RET mutation, Von Hippel-Lindau disease, Neurofibromatosis type 1
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