Biochemistry

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Section 1 - DNA Replication (17:27)
TOPICS: Complementary, cytosine, adenine, guanine, thymine, histones, nucleosome, first histone (H1) (linker), chromosome, heterochromatine, euchromatin, DNA transcription, histone methylation, histone acetylation, DNA replication, helicase, replication fork, single-stranded binding proteins (SSBPs), origin of replication, primase, 3’ end, primer, DNA structure, DNA polymerase III, DNA polymerase epsilon, deoxynucleotides, exonuclease, leading strand, lagging strand, Okazaki fragments, DNA polymerase I, DNA polymerase delta, RNA primers, DNA ligase, topoisomerase, supercoils, fluoroquinolones, irinotecan, topotecan, etoposide, teniposide, telomerase, gyrase
Section 2 - DNA Repair (9:09)
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Section 3 - Transcription (14:34)
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Section 4 - Translation (10:44)
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Section 5 - DNA Mutations (11:08)
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Section 1 - Cell Cycle (7:51)
TOPICS: Cell cycle phases, G0 phase, G1 phase, S phase, G2 phase, mitosis (M), prophase, chromosomes, spindle fibers, metaphase, anaphase, telophase, daughter cells, cell types, permanent cell, stable (quiescent) cell, labile cell, cytokinesis, growth, DNA synthesis, cell cycle regulation, cyclins, cyclin dependent kinases (CDKs), cyclin-CDK complex, phosphorylation, retinoblastoma protein (Rb), transcription factor, E2F, cellular division, cell cycle progression, cyclin D1, mantle cell lymphoma, retinoblastoma, Li-Fraumeni syndrome, p53, osteosarcoma, regulation of G1/S phase transition
Section 2 - Cell Structure (13:56)
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Section 3 - Connective Tissue (11:38)
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Section 1 - PCR (9:38)
TOPICS: DNA bands, electrophoresis, DNA amplification, DNA template, adjacent regions, flanking sequences, DNA primer, DNA polymerase, thermostable, deoxynucleotide triphosphates, denaturing, annealing, elongation, primers, target region, extension, free deoxyribose base, polymerase chain reaction (PCR), real time polymerase chain reaction (PCR), reverse transcription polymerase chain reaction (PCR), DNA fluorescent, threshold, complementary DNA (cDNA), introns, mRNA, reverse transcriptase, exons
Section 2 - Blotting Procedures (4:02)
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Section 3 - Flow Cytometry (3:19)
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Section 4 - Microarrays & ELISA (4:10)
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Section 5 - Karyograms & FISH (3:31)
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Section 6 - CRISPR Cas9 & Molecular Cloning (4:07)
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Section 1 - Genetics Overview (12:54)
TOPICS: Alleles, genotype, phenotype, variability, phenotypic manifestations, tumor suppressor genes, gametes, mutations, locus, loci, mitochondrial genomes, dominant, codominance, incomplete penetrance, variable expressivity, pleiotropy, anticipation, loss of heterozygosity, germline mosaicism, somatic mosaicism, locus heterogeneity, allelic heterogeneity, heteroplasmy, dominant negative mutation, neurofibromas, retinoblastoma, Gomori trichrome stain, breast cancer, BRCA1 gene, neurofibromatosis type 1 (NF1), homocystinuria, Marfanoid habitus, Huntington disease, retinoblastoma, Turner syndrome, McCune-Albright syndrome, albinism, beta-thalassemia, mitochondrial disorders
Section 2 - Imprinting and Uniparental Disomy (11:14)
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Section 3 - Linkage Disequilibrium (7:00)
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Section 4 - Pedigrees (11:14)
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Section 5 - Hardy Weinberg Principle (11:05)
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Section 6 - Autosomal Dominant Diseases (5:42)
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autosomaldominantdiseasesSection 6.1 - Autosomal Dominant Diseases (4:17)
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Section 7 - X linked Diseases (4:26)
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x linked recessive diseasesSection 7.1 - X linked Recessive Diseases (3:36)
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rett syndromeSection 7.2 -Rett syndrome (3:16)
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Section 8 - Autosomal Recessive Diseases (9:58)
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Section 9 - Trinucleotide Repeat Disorders (6:59)
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huntington diseaseSection 9.1 - Huntington Disease (5:05)
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myotonic dystrophySection 9.2 - Myotonic Dystrophy (3:21)
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fragile x syndromeSection 9.3 - Fragile X Syndrome (2:50)
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friedreich ataxiaSection 9.4 - Friedreich Ataxia (6:54)
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Section 10 - Autosomal Trisomies (10:14)
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down syndromeSection 10.1 - Down Syndrome (7:19)
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edwards syndromeSection 10.2 - Edwards Syndrome (4:21)
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patau syndromeSection 10.3 - Patau Syndrome (3:51)
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Section 11 - Sex Chromosome Disorders (8:28)
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turner syndromeSection 11.1 - Turner Syndrome (5:06)
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klinefelter syndromeSection 11.2 - Klinefelter Syndrome (4:55)
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Section 12 - Microdeletion Syndromes (4:40)
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cri-du-chat-syndromeSection 12.1 - Cri-du-chat Syndrome (3:10)
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williams syndromeSection 12.2 - Williams Syndrome (3:10)
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Digeorge syndromeSection 12.3 - DiGeorge Syndrome (6:23)
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Section 1 - Hexokinase & Glucokinase (12:30)
TOPICS: Enzyme terminology, kinases, phosphate groups, phosphatases, phosphorylases, inorganic phosphate, ATP, dehydrogenases, redox reactions, mutase, functional group, hydroxylases, hydroxyl group, carboxylases, Michaelis-Menten kinetics, maximum speed of a reaction (Vmax), concentration of a substrate that permits the enzyme to achieve half of Vmax (Km), affinity of the substrate for the enzyme, glucokinase, hexokinase, glucokinase and hexokinase curves, glucose-6-phosphate, insulin, energy, liver, blood glucose concentration, fed state, fasting state, glucose utilization
Section 2 - Glycolysis (12:25)
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Section 3 - Pyruvate (11:13)
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Section 4 - TCA Cycle (9:40)
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Section 5 - ETC (9:42)
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Section 6 - Gluconeogenesis (12:27)
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Section 7 - Glycogen (14:21)
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von gierke cori diseaseSection 7.1 - Von Gierke & Cori Disease (7:04)
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pompe mcardle diseaseSection 7.2 - Pompe & Mcardle Disease (6:39)
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Section 8 - Fructose Metabolism (9:12)
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Section 9 - Galactose (8:50)
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Section 10 - HMP Shunt (8:12)
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Section 11 - Fat Metabolism (15:41)
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Section 12 - Ketones (7:41)
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Section 13 - Ethanol (8:10)
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Section 14 - Lipid Transport (25:32)
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Section 15 - Homocysteine (8:55)
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Section 16 - Purines & Pyrimidines (14:36)
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Section 17 - Ammonia (10:32)
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Section 18 - Amino Acids (13:56)
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Section 19 - Lysosomal Storage Diseases (8:26)
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tay sachs niemann pick diseaseSection 19.1 - Tay-Sachs & Niemann-Pick Disease (4:46)
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fabry diseaseSection 19.2 - Fabry Disease (4:33)
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metachromatic leukodystrophySection 19.3 - Metachromatic Leukodystrophy (3:06)
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krabbe diseaseSection 19.4 - Krabbe Disease (3:23)
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gaucher diseaseSection 19.5 - Gaucher Disease (2:55)
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hurler hunter syndromeSection 19.6 - Hurler & Hunter Syndrome (6:43)
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Section 20 - Nutrition (11:45)
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thiamineSection 20.1 - Thiamine (B1) (6:42)
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riboflavinSection 20.2 - Riboflavin (B2) (1:56)
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niacinSection 20.3 - Niacin (B3) (7:39)
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pantothenic acidSection 20.4 - Pantothenic Acid (B5) (2:44)
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pyridoxineSection 20.5 - Pyridoxine (B6) (8:04)
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BiotinSection 20.6 - Biotin (B7) (3:49)
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folateSection 20.7 - Folate (B9) (5:04)
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cobalaminSection 20.8 - Cobalamin (B12) (7:03)
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vitamin cSection 20.9 - Vitamin C (6:28)
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vitamin aSection 20.10 - Vitamin A (8:55)
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vitamin dSection 20.11 - Vitamin D (6:46)
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vitamin eSection 20.12 - Vitamin E (5:16)
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vitamin kSection 20.13 - Vitamin K (7:12)
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zincSection 20.14 - Zinc (2:45)
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