TOPICS: Nitrogenous bases, DNA, RNA, purine synthesis, adenine guanine, pyrimidine synthesis, cytosine, thymine, uracil, ribose-5-phosphate, orotic aciduria, UMP synthase, megaloblastic anemia, hyperammonemia, uridine, dTMP, folate, purine salvage pathway, guanosine monophosphate (GMP), inosine monophosphate (IMP), adenosine monophosphate (AMP), DNA synthesis, RNA synthesis, adenosine deaminase deficiency, adenosine metabolites, T lymphocytes, severe combined immunodeficiency (SCID), Lesch-Nyhan syndrome, orotic aciduria, nucleotides, hypoxanthine guanine phosphoribosyltransferase (HGPRT), uric acid, gout, self-mutilation, intellectual disability