TOPICS: Single palmar crease, increased maternal age, nondisjunction, Alzheimer’s dementia, Hirschsprung’s disease, increased space between first two digits, nuchal translucency, fetal ultrasound, duodenal atresia, atrioventricular cardiac defects, acute myelogenous leukemia (AML), acute lymphoblastic leukemia (ALL), epicanthal folds, brushfield spots, low estrogen, maternal serum alpha-fetoprotein (MSAFP), beta hcg, inhibin A